People are overblowing the SBI stuff, imo. The development has been reported to have been a wreck for several years, a couple years ago there was this emergency stop of what was going to be a total GAAS game that was walked back later. Screenshots of the UI and weapons were a total mess. They likely had to stop and start over development so many times that even Harley Quinn's nerfed ass compared to previous Arkham games probably was not a deliberate choice but developers in a rush. Yeah SBI probably mucked with the story some but it's just the rotten cherry on a dogshit sundae. Hyper-focusing on SBI detracts from the other problems, like how this whole thing boils down to companies wanting their own Fortnite and their own Call of Duty and they keep burning existing IPs like effigies trying and failing.
It says they're only doing it for nonviolent cases, so presumably someone just acting loopy because he forgot his meds and thinks he's Jesus, etc. In which case it's probably better to send someone actually trained to handle mentally ill people rather than send the cops who don't have much mental health training that doesn't involve drug abuse. It puts optimally trained people on these cases and frees up police from having to deal with these frivolous cases.
I'm probably not going to bother with 99% of isekai from now on because they are so hellbent on showing off how absurdly OP the MC is that they fail to provide actually good conflict and the side characters are boring as shit.
Mushoku Tensei still has my interest because even though the MC is strong, he doesn't steamroll everything he comes across and it feels like he could get squashed like a bug if he's not careful.
It's really obvious what they are doing. They are using homosexuality to spearhead the attack of exposing their children to any other non-Muslim things. They want to keep their children insulated in Sharia Law, even though these disgusting hypocrites chose to live in a Western country.
Druckmann is saying that Sony not only chopped up and botched his answers but also added lines that he never said. So this isn't just "whoops" but Sony lying.
And I don't like Druckmann but if he normally sniff his own farts, I don't see why he would suddenly lie and claim Sony put words in his mouth.
I liked Furiosa in Mad Max Fury Road....but not enough to pay to see a prequel movie about her in theaters.
I also don't like Anya Taylor-Joy, her eyes are so wide they're migrating to the sides of her head and she looks like a fake person spat out by an AI. It doesn't help she got that cheek fat suction surgery to make her eyes look even bigger, but it's going to prematurely age her in just a few years.
Hopefully the failure of Starfield was enough to shake Bethesda up and realize they need to course-correct. I haven't done much analysis of why Starfield did not live up to even modest expectations (for a game that was supposed to be the company's original IP magnum opus) but a major factor seemed to be how the game was essentially made by several divisions that did not collaborate with each other and the final product crudely stitched together.
I don't have much faith, never pre-order, etc. but it would be nice if one of these goddamn AAA Western game companies would wake the fuck up before they burn everything they have to the ground.
I don't think it'll go through just for the fact nobody wants to pay to redraw state lines. Looking at the map of the counties, there is a huge awkwardness with the county lines, with some strictly Oregon counties still being within the proposed Greater Idaho. That's a lot of land and property to move, sell, etc.
13 counties making 10% of the population voting in favor at 53%. Unfortunately, the rest of Oregon will probably just Occam's Razor it and tell the 5.3% of the population that wants to join Idaho to move to Idaho themselves.
Yeah they just scrapped data from 90 million patients. There was no control for trannies that never had surgery. It just shows that trannies who've had sex changes have a higher suicide attempt than the general population, but without data comparing it to no-surgery trannies this isn't anything new.
Some animal species have observed to commit homosexuality but idk how the hell they would claim there are trans animals? ....Oh wait, they're going to claim hermaphrodites are trans, aren't they? Animals that are either both sexes, or animals that can change from one sex to the other at some point in their lives (or due to pollution).
The entire Fate franchise is about bastardizing historical characters and turning them into waifus. So there wouldn't be any fans of Fate to suddenly be upset about this particular videogame. Anyone who gives a damn about historical accuracy knows that Fate is Not For Them.
The structures of mRNA and non-coding RNAs are different. Way different. In biology, structure is function.
They use the same nucleotide building blocks, yes (Uracil, Adenine, Cytosine, and Guanine) but even those building blocks are used differently. For example, with microRNA this nucleotide sequence needs to be very specific for it to fold and become double-stranded and form a hairpin loop so it can be recognized by the necessary protein complex, attach, and allow the microRNA to guide it to its target. mRNA does not have such sequences. And the specific nucleotide sequence requires several nucleotides in a row, so a spontaneous mutation wouldn't wouldn't be enough to induce the formation of one.
Why other structures are keyed to interact with RNAs also depends on the modifications an RNA has, rather than its sequence. mRNA needs to have a special methylated guanosine attached to the front as well as a chain of adenines known as the poly-A tail to the end. They both keep the mRNA stable and are recognition sites for the mRNA to be properly used. If the mRNA becomes unstable and breaks apart, it gets targeted for degradation because pieces will now no longer have these protective caps.
rRNA, also known as ribosomes, are so structurally different from mRNA it would be impossible for one to turn into the other spontaneously. Same with lncRNA. tRNA is also capped with specific tags on its ends that are completely different from mRNA, in addition to having essential tertiary structure. And to get these tags occurs during the synthesizing of the specific type of RNA, so you can't just have some random RNA floating by get the wrong tags.
Basically, non-coding RNAs have significantly different structures and these structures are obtained by very specific sequences that mRNA just doesn't have. This doesn't rule out mRNA doing other things - like there is some evidence mRNA-based jabs can undergo reverse transcription - but mRNA to non-coding RNA, nah.
mRNA, even highly unstable mRNA, behaving like non-coding RNA, is not eminently possible. I even tried to check for any evidence of this occurring, nada. It's so improbable it's like talking about alchemy. It's like throwing a bunch of car parts into a tornado and having a road-certified car spat out.
It's money.
It's the "influencer" business model. They make money off of social media. They do this by getting attention.
This is also why being a "traditional wife" influencer is a paradox: these women are making money (some of them a LOT of money) by pretending that their husbands are the only ones who make money.
People are over-focusing on the black samurai. I'm not saying the black samurai insertion should be ignored, but there is so much more
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The co-protagonist is Naoe, who is an OC girlboss of historical figure Naoe Kanetsugu
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It's a single player game that requires online to install
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All the fucking $130 complete edition, season pass, live service bullshit
So the Confederate flag is a Jewish flag?