Maybe, but most likely not. There are venomous animals which can be quite readily digested because the dangerous venom they carry simply doesn't survive the stomach barrier. They can only cause damage when able to properly introduce venom to body tissue and the circulatory system since many venoms are paralysing agents or necrotic.
Poisonous creatures however are the ones which would cause problems there and there are some rare animals which are both venomous and poisonous at the same time, but midges aren't going to be one of them when carrying a vaccine. No matter how many you or something else consumed there would be no chance a vaccine made it through the acidic environment of a stomach.
That mechanic is more commonly referred to as a "photonic fence" and uses a 2 stage laser method of low powered identification scanning laser and higher power killing lasers. Comparatively the energy difference is minimal to almost everything except something as frail as a mosquito where even just a few degree of energy change can be significant, hence how and why some bees boil invading hornets alive by dog piling said hornets with numerous bee drones and vibrating in unison to create a localised increase in temperature that kills the invader.
Precisely what is scanned for varies on a species by species basis as it's precise enough to differentiate between male and female mosquitoes. Since only female mosquitoes feed on blood and other methods of mosquito control such as modified sterile males affect different targets integrated pest management [IPM] strategies would be unhampered by photonic fences engaging in active use.
It's never likely to be a perfect solution though hence why both direct eradication through methods such as the photonic fence and vector based strategies such as vaccines and are being looked at together.
Excellent, another round of one of my pet projects, namely mosquitoes and pest control.
Regarding species the topic here is initially Malaria and then some notes about similar work involving Leishmaniasis. Both are caused by protozoan parasites of different Genera, the former being the Plasmodium with the latter being Leishmania, which is certainly far easier to pair with its related disease.
What's important about protozoan vs other causes of insect borne diseases are just how much larger they are vs bacterium and viruses.
Imagine the difference between a motorbike, a humvee, and a double decker bus. Protozoa are the double decker bus, viruses are the motorbikes, and just like how a motorbike can get in between things neither the bus or humvee can the viruses can infect along vectors that protozoan are simply too large to copy.
This difference in parasite can be significant enough to warrant drastically different control methods because in the case of Malaria carriers no Anopheles spp. or other Malaria carrying mosquito is ever born carrying the diseases, they have to feed on an already infected host first then transfer it to another. Whereas something like Dengue which is transmitted by a virus can be passed on from generation to generation in mosquitoes so newly hatched Aedes aegyptii for example are already infectious. This is as highlighted above because of the size difference in the parasites. Dengue and other viruses are small enough to undergo vertical transmission from mother to offspring, Malaria is too large however.
So in order to avoid infection with Malaria you need to prevent the known hosts from feeding on an infected host and/or then transferring the diseases to healthy hosts, a somewhat easier process than trying to prevent any and all Dengue infections from instantly infecting vectors feeding just the once.
Precisely how you prevent those hosts doing things in the first example varies from vaccinating healthy individuals on the off chance any future mosquito bite might be the one with the diseases, to vaccinating against the actual mosquito itself - It's possible to create a vaccine that targets the mosquitoes carrying the disease so that if they feed on such vaccinated hosts the mosquitoes die preventing subsequent transmissions.
There's also the "Star Wars" option of using a photonic fence to simply zap your target vector out the air before it reaches anyone or anything to bite, however the infrastructure required for these suffers from local problems of lack of electricity and flat out theft of the devices 🙄
Also worth pointing out Leishmaniasis isn't just spread by mosquitoes [Culicidae], there are also horse-flies [Tabanidae] and midges [Ceratopogonidae] so such control methods aren't even that absolute and would require broader control methods than simply focusing on "the mosquito problem", and if people think mosquitoes are bad then they've never had the displeasure of being bitten by a horse-fly or swarmed by midges.
Mosquitoes can and will bite you and you won't know it until later if ever. You WILL know when a horse-fly bites you, it's unironically like being stabbed it's that sudden and significant a sensation. Midges however are in the completely opposite end of any such a spectrum and will not only be impossible to feel biting you but do so in such numbers you won't realise it has happened until you're already covered in countless bites because they're that small in comparison. Mosquitoes can be as large as 18mm in length and you might at least hear coming and going, but midges top out at around 3mm so good luck seeing them let alone hearing them.
The notes about consent aren't wrong though, and while the proposed method would work well against controlling Malaria and then other diseases there is a whole list of issues this then brings up, the least of which being yet again a decrease in mortality in areas already suffering from overpopulation and lacking resources. Then there's the far more sinister point about once this method is actually finalised it's not much additional work to change the payload to something dangerous and weaponise the vaccine vector, which some will suggest is the point in the first place.
That thing Geralt and Shani specifically talk about in the Heart of Stone DLC in Witcher 3? That thing the current devs clearly have zero fucking clue about because they never actually played any of the previous games otherwise they would know they're retreading old and done material? No fucking surprise there 🙄 actual fucking tourists and parasites.
The "problem" with Firefly is that there's just enough of it to remain a good thing, sealed away forever as a dozen or so episodes, and the movie. Much like actors who remain "forever young" when they die far sooner rather than later, the lack of additional content means fewer chances to fuck things up. Look at Marilyn Monroe vs Elvis for example, Monroe will always be the picture of beauty to those who remember her, while at the end Elvis was overweight and damaging his image. Firefly may have gone the same way since by the time "season 1" ended a lot of character background has already been revealed, apart from Book and Inara. So anything season 2 might have tried to explore would run the risk of being far more harmful than beneficial to the story and characters overall. With lots more barefoot young women ofc since it was still Sensitive Joss Whedon back then who hadn't yet been outed as the footfag and adulterer he's known as now.
Space Precinct was a show l loved as a kid. The cyborg episode was amazing when it just showed up and started wrecking shit. Very cliché in the end, but then that's what most shows do, especially for you episodes where all the plot armour suddenly stops working.
On the off chance this leads to some new ideas to try recipe wise, u/BulbasaurusThe7th do you have any input on making coleslaw?
If anyone else also has input/recipe ideas please do post them below.
Nothing.
I got Stellaris years ago and the mod scene there means I'll probably be playing it forever.
On top of that, X-Com 2 which is in a similar xeno infested boat, there are cracks, private servers and a whole host of other games out there which mean not only do I have more time than money or sense to spend, but there aren't any actual monetary costs involved now either.
I've had doxycycline when doing work in the tropics before, my main issue has always been I'm utterly rubbish at taking meds since I can't swallow them without some kind of aid.
There are other options to treat malaria however it swaps between preventative methods and curative, where Doxy being something you take daily would be the former, while something from the Artimicinines would be the latter. Unfortunately resistance to treatments eventually renders things redundant despite how effective they might have been at first. Artimicinines were groundbreaking in their effectiveness at first but slowly lost potency.
As for weaponising vectors it's always very likely going to be in the mind of someone close enough to these kind of projects because they know the work done treating a problem like this will lead to a lot of the work relating to their own personal porjcets being done without requiring specific research and funding. Co-opting existing studies and methods is always cheaper and easier to then apply new targets to, similar to how in the entertainment industry popular franchises get taken over and infected by talentless hacks trying to push their own agendas because without the existing audiences you get things like Concord which flop immediately.