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18
Did you know that poop transplant is a thing? Research shows young mouse poop transplanted into old mice retards aging in old mice (archive.ph)
posted 125 days ago by Mpetey123 125 days ago by Mpetey123 +18 / -0
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▲ 22 ▼
– YouAreAPirate 22 points 125 days ago +22 / -0

Aren't they already doing this in humans already? I thought poop transplants were used in humans for certain diseases.

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▲ 11 ▼
– freedomlogic 11 points 125 days ago +11 / -0

Yeah I was thinking they have been doing this for like 30 years now, and then I made the mistake of googling it.

Fecal microbiota transplantation (FMT), or stool transfer therapy, originated in 4th-century China (c. 300-400 CE), where human fecal suspensions were used to treat severe diarrhea and food poisoning. The first documented use in modern Western medicine occurred in 1958 by surgeon Ben Eiseman to treat pseudomembranous colitis.

4th Century China: Known as "yellow soup" or fecal suspension, it was used by Ge Hong to treat diarrhea.

TIL

But the theory is sound...

The human body is composed of roughly 30 to 39 trillion bacteria and approximately 30 trillion human cells, resulting in a roughly 1:1 to 1.3:1 ratio of microbes to human cells. While microbes outnumber or equal human cells, they only account for about 0.2 kg to 2 kg of total body mass, meaning by weight, the body is over 99% human.

It kinda disturbs me to think I have some microbes living in the pores of my eyebrows.

The microscopic creature that lives in human hair follicles, including the eyebrows and eyelashes, and is commonly described as never pooping (or lacking an anus) is the Demodex mite (specifically Demodex folliculorum and Demodex brevis).

The "No Poop" Myth/Fact: For a long time, it was believed that Demodex mites lacked an anus and therefore stored all their waste throughout their entire life, releasing it all at once when they died. However, a 2022 study found that they do have an anus, but they are often still cited as having a "rudimentary gut" that rarely discharges waste, making the old description popular in science communication.

But its been linked for a while now that people with large concentrations of "bad gut bacteria" have a slew of health problems, its also been proven your stomach/gut has a "mini brain" which coordinates digestion.

What is it? The ENS is a vast,, complex network of over 100 million to 600 million neurons—more than in a cat's brain—embedded in the walls of the gastrointestinal tract, stretching from the esophagus to the rectum.

It also turns out that ethnicity's have their own microbiome flora as well.

Scientific studies indicate that while the core human gut microbiome is similar across the globe, distinct variations exist between different ethnicities and geographic populations. These differences are largely driven by a combination of dietary habits, cultural practices, lifestyle, environmental exposures, and, to a lesser extent, host genetics.

Whats interesting too, is the "bad bacteria", has figured out a way to secrete a substance that makes you feel hungry so that you keep feeding it.

Yes, research indicates that imbalanced or "bad" gut bacteria can secrete substances and produce metabolites that increase hunger, trigger cravings, and sabotage feelings of fullness. When the microbiome is in a state of dysbiosis (an imbalance between beneficial and harmful bacteria), it can manipulate host behavior to favor the consumption of foods that help those bacteria thrive.

Prolly worth mentioning, we are literal walking bacterial colony's, we need them to survive, so I would like to keep mine. But within 15 minutes of someone stepping into a room, they will start to "infect" the space around them.

Human occupancy rapidly changes the microbial composition of indoor air, with studies showing that individuals emit a "microbial cloud" of bacteria and fungi—ranging from (10^{6}) to (10^{7}) particles per person per hour—that can be detected in surrounding air within a very short timeframe. While specific, distinct identification of an individual's cloud often takes 1.5–4 hours in controlled studies, the total airborne bacterial load significantly increases almost immediately upon entering a room.

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▲ 12 ▼
– ArchRespawnsAgain 12 points 125 days ago +12 / -0

The people pushing this are probably full of shit.

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▲ 7 ▼
– tralbolh 7 points 124 days ago +7 / -0

Isn't this fairly common practice for old folks and their grandkids poop to deal with the side effects of harsh antibiotics wiping out their gut fauna?

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▲ 7 ▼
– Butttoucha9k 7 points 125 days ago +7 / -0

Your poop retards

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▲ 6 ▼
– deleted 6 points 125 days ago +6 / -0
▲ 5 ▼
– SocraticMethod1 5 points 125 days ago +5 / -0

......why did they do this?

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▲ 13 ▼
– ernsithe 13 points 125 days ago +13 / -0

There are diseases where you gut microbes have been so destroyed, that they try to re-establish their population from a donor. So as ridiculous as it initially sounds, this is an area of study.

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▲ 7 ▼
– Ender910 7 points 125 days ago +7 / -0

Antibiotics are supposedly another potential variable that can cause problems with gut microbiology too. Although that's probably addressable with probiotics, unless someone has a long history of really heavy antibiotic-use.

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▲ 6 ▼
– freedomlogic 6 points 125 days ago +6 / -0

Yeah, when I was a kid I took antibiotics every summer for swimmers ear, coincidentally it was then I actually started getting fat. I also knew a guy with IBS, which is funny because he was a driver so every 2 hours we would have to stop somewhere.

But I suspect that had to do with the fact he was a drunk. Every night he had a bottle of vodka and would then proceed to drink the entire thing. His gut hated him, im sure. He also used to work for the canadian revenue agency and would laugh telling me some old stories about busting people for tax evasion.

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▲ 5 ▼
– SocraticMethod1 5 points 125 days ago +5 / -0

Ok that's reasonable.

But why do these people reporting on it have to always use such childish or perverted terms to report results?

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▲ 3 ▼
– AlfredicEnglishRules 3 points 124 days ago +3 / -0

Did it all for shits and giggles.

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▲ 3 ▼
– RadiateTonight 3 points 124 days ago +3 / -0

Why don't the grow the stuff and transplant that instead?

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▲ 3 ▼
– ChippingToe 3 points 124 days ago +3 / -0

Why does the old mouse have to be retarded?

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▲ 3 ▼
– theaustrianpainter 3 points 124 days ago +3 / -0

This is fairly old medicine.

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▲ 2 ▼
– MattTheBlack 2 points 124 days ago +2 / -0

Yes

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