I don't even know
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The example I've always used is every other year or so someone goes to Africa on safari or whatever and gets mauled by a lion or a hippo. Now, you would think with all the signs and guides telling them to stay in the vehicles for their own safety they would, but almost every time, they get out. Seems to me that evolution, fight or flight, or goddamn self preservation would make them follow directions but it happens.
This is exactly what one would predict would happen when "natural selection" gets shut off. It's basically summed up in the introduction to Idiocracy.
Other forms of selection take over, however. The selfish and underhanded, the clever who know how to keep their heads down and game the system, the real rotters, the workshy, start doing well. So you can expect a social animal's society to fall apart, and a dieback to happen. The healthy in both body and mind get preyed on by them, and burdened by the needy losers. If any population(s) survive an extinction event, they may have to start over again (depending on the level of tech they're left with - if nothing, you're back to simple natural and sexual types of selection.)
Black people hahahahaha