I was hesitant about Blade Runner 2049 until I saw it. However, the original had a possibility for a sequel given the movie ends with the main characters on the run from the police.

Gladiator has no reason to have a sequel. The plot was wrapped up, the main character dies at the end along with the antagonist, and there wasn't another character that had a plot line that needed to go somewhere.

I am looking forward to Dune. Despite the race swapping, the first one was pretty good, and Villeneuve is basically the only really good director out right now.