It's speculated that Michaelangelo may have been austic, and for him, it seems to fit (poor hygiene, insane dedication to his work, insane work hours, erratic social life, etc.).

Leonardo autistic? I doubt it. Was he gay? Maybe, who knows.

The "-ism" people love to claim people in the past, and they can't concieve of a world which doesn't exactly conform to modern standards and modern sensibilities. Male friendship?!--must be gay!

My favorite. Raphael. Guy had good taste! https://en.wikipedia.org/wiki/La_Fornarina