Sadly, I could see them doing that, but she'd also have to "out-Indy" Indy. She'd prove to be better at archaeology, physicality, and one-liners by showing up his old ass at every turn, and by the end of the movie he'd either turn over the hat and whip to her, or at some point during the film he straight-up dies and she takes them up herself to finish out the adventure. Wouldn't put it past Woke Hollywood to do so, considering how much they cocked-up the sequel trilogy for Star Wars.