A unilateral blockade.
Nuclear weapons cannot be used for most conflicts.
But about 30 middle East countries discovered they can bring the highly leveraged US to their knees by mining/drone attacking the two middle east shipping chokepoints.
Strait of Hormuz — Iran, Oman, United Arab Emirates; very near: Saudi Arabia, Qatar, Bahrain, Kuwait, Iraq
Bab el-Mandeb — Yemen, Djibouti, Eritrea; very near: Saudi Arabia, Somalia, Egypt, Sudan, Oman
(maybe add the straits of singapore too)
To the nationalists, this is a great thing.
International trade has been an inarguable disaster. And once we've severed ourselves out of being the committed fist of globalism, the United States actually needs very little from such trade. We possess the capacity to be a largely independent and self sufficient nation.
For all their posturing it was Europe and China that needed the Strait open. It is they who depend on international shipping.
The problem is twofold at a minimum. Our nations stock has been so diluted with jeets and browns, trying to rebuild a strong national base almost needs to happen before dialing back global trade.