Actually they just refuse to 'end' the study if they don't like the results. Eventually their funding will run out and they just won't release the findings stating lack of funding.
And they end their 'study' prematurely if they do like the result so far, claiming that it is 'unethical' to not let Big Pharma profit from the control groupdeny the control group the great benefits of the medicine.
For a layman, what is the significance of a principle trial?
And are they obligated to publish anything about their results?
Principle is just a name. It's a large-scale randomized controlled trial not directly funded by drug companies. The "gold standard".
There's probably some UK freedom of information type thing they are figuring out how to game so it won't be released for 66 years...
Actually they just refuse to 'end' the study if they don't like the results. Eventually their funding will run out and they just won't release the findings stating lack of funding.
And they end their 'study' prematurely if they do like the result so far, claiming that it is 'unethical' to
not let Big Pharma profit from the control groupdeny the control group the great benefits of the medicine.