It gets really stupid. Vampires are implied to be european slavers but then the big baddie's right hand is a black vampire wearing go-go boots.

Yoruba gods are real (Anette is a descendant of two of them, of course) and the africans still got enslaved somehow. Imagine having control over metal and earth and still get mogged by a bunch of people with guns...

Elizabeth Bathory is actually Sekhmet (furry head and all) and she blocks the sun to get back at Ra, which is retarded on so many levels I don't know where to begin. For starters it reframes "muh rich people should rule" natural order shit, is she actually referencing the Ma'at? Sekhmet is not evil, there are evil egyptian gods associated with darkness and a bone to pick with Ra (Apophis) so why pick her, Ra's servant and Hathor's alter-ego? And again, if gods are real how the fuck did egypt decay? She says vampires have had to tolerate alliances with humans for reasons but she is literally a god and it's implied other gods are real so, how? What could even humans do to them?

It's implied Olrox is Quetzalcoatl and the reason he wants to stop Elizabeth is because Europeans conquered his people but as I pointed out she's actually Sekhmet so his motivation (weak as it is) doesn't really makes sense anymore. Oh, and he is a gay homo with the bara soldier... why? Do the writers know what whas the punishment for gays in the aztec culture? He also kills Richter's mother because she killed his mohican lover (also gay) and the show doesn't really portraits him in the wrong for that. It also raises questions like were pre-columbine gods real? Are they vampires and that's why they need sacrifices? Etc. Why use Quetzalcoatl anyway, there are moon demons that drink human blood in aztec mythology, you know?

And course the christian God is useless, the extend of his power is relegated to kinda scorching vampire's skin when they touch a cross... no holy water, no bible, no cross-erang nothing. Magic is relegated to basic fire balls, ice and blue fire (that's Richter's item crash substitute apparently).

To add salt to the injury Maria's Four Symbols get demoted to being just animals she summons. And one of the phoenix/red bird dies... and she gets another one off-screen... also, no blue dragon (seiryu) because reasons. I guess the writters didn't want an european girl to have magic powers based on asian mythology.

And that's just how bad religions/mythos get threated, other aspects like the writting shit too. In fact, I think the show's only reedeming quality is that it looks nice...