It's just mRNA inside a lipid shell. Lipid shell makes contact with the cell membrane and merges like two soap bubbles.
The main CRISPR protein Cas9 is huge at 3x larger than average protein. They didn't jam it into a bubble along with instructions when all they needed was the mRNA.
The mRNA is all you need, it's purpose in the cell is to make proteins. What they did do is use methylated Uradine which limits the cell's normal process of destroying mRNA after it's used so cell keeps making lots and lots of spikes instead of just one or a few copies.
Yes normally when the cell wants to make any protein it copies the instructions from DNA in the nucleus into mRNA, the mRNA instructions go out into the main part of the cell, find a ribosome which manufactures the protein, and then the cell destroys the mRNA because it only wants one of the protein not a million of them.
So the pfizer/moderna is just mRNA instructions to make spike protein, except with unnatural tweaks to make them keep producing it over and over again. This is one of the main problems with the technology itself and means you can't predict the dose an individual gets, the other big problem being the nanolipids will merge with and reprogram any cell anywhere in the body.
Of course it's never that simple because retroviruses have given us the 'ability' to go backwards from mRNA back into DNA and somehow parts of the vaccines get inserted into at least liver cells' DNA. It's easy to believe they did this on purpose, but could just be unfortunate chance.
CRISPR is a tool from bacteria that can chop pieces of DNA into parts based on a program. So it's used a lot in research to manipulate DNA, like at Wuhan to chop parts from one virus and add them to another one to make a frankenvirus.
It's just mRNA inside a lipid shell. Lipid shell makes contact with the cell membrane and merges like two soap bubbles.
The main CRISPR protein Cas9 is huge at 3x larger than average protein. They didn't jam it into a bubble along with instructions when all they needed was the mRNA.
The mRNA is all you need, it's purpose in the cell is to make proteins. What they did do is use methylated Uradine which limits the cell's normal process of destroying mRNA after it's used so cell keeps making lots and lots of spikes instead of just one or a few copies.
Oooohkay I see my confusion here. The mRNA itself is what was manufacturing the spike proteins, correct?
Yes normally when the cell wants to make any protein it copies the instructions from DNA in the nucleus into mRNA, the mRNA instructions go out into the main part of the cell, find a ribosome which manufactures the protein, and then the cell destroys the mRNA because it only wants one of the protein not a million of them.
So the pfizer/moderna is just mRNA instructions to make spike protein, except with unnatural tweaks to make them keep producing it over and over again. This is one of the main problems with the technology itself and means you can't predict the dose an individual gets, the other big problem being the nanolipids will merge with and reprogram any cell anywhere in the body.
Of course it's never that simple because retroviruses have given us the 'ability' to go backwards from mRNA back into DNA and somehow parts of the vaccines get inserted into at least liver cells' DNA. It's easy to believe they did this on purpose, but could just be unfortunate chance.
CRISPR is a tool from bacteria that can chop pieces of DNA into parts based on a program. So it's used a lot in research to manipulate DNA, like at Wuhan to chop parts from one virus and add them to another one to make a frankenvirus.