The mRNA technology isn't really the problem. If the mRNA was designed to make the entire virus as an inert shell rather than just the spike protein it would probably be safer and definitely give better immunity because the capsid mutates much slower than the spike- it's almost like it was designed to not last long.
The J&J vaccine is an mRNA vaccine but it has storage and transport requirements of a traditional vaccine because it delivers the mRNA through an adenovirus rather than a nanolipid.
That's not true. Here's an archive of the same page from 2015. https://archive.is/4OKBO#selection-687.84-687.85 mRNA has always been a mechanism to move instructions from the actual DNA to outside the nucleus. It's never been a mechanism to rewrite DNA (although it is likely that there have been attempts to edit DNA that involve mRNA, but that is not the normal function of mRNA). You are fucking wrong. I took AP biology which isn't much but it's enough to know what mRNA is.
To
translate and form the chemical bonds in protein, the bacterial cell
deploys a piece of extremely complex equipment. The synthesis of
proteins is a two-stage process, since the protein sub-units are
assembled and polymerized, not directly on the gene, but on small
particles in the cytoplasm which serves as assembly lines. the deoxy-
ribonucleic acid text of the gene is therefore first transcribed into
another species of nucleic acid, the so-called ribonucleic acid, by
means of the same four-sign alphabet. This copy, called the 'messen-
ger', associates iwth the particles in the cytoplasm and brings them
the instructions for assembling the protein sub-units in the order
dictated by the nucleic-acid sequence.
Page 276
The logic of life : a history of heredity
by Jacob, François, 1920-2013
You do need an account to 'borrow' the book. And maybe archive.org is making very convincing edits to their scanned books but that seems wildly unlikely since most people won't investigate past the first internet rag that comes up on google.
The mRNA technology isn't really the problem. If the mRNA was designed to make the entire virus as an inert shell rather than just the spike protein it would probably be safer and definitely give better immunity because the capsid mutates much slower than the spike- it's almost like it was designed to not last long.
We already have a tool to force your cells to make an entire virus - it's called a virus.
Well, yeah, but ideally it would create a virus that lacks the means to create a virus.
The J&J vaccine is an mRNA vaccine but it has storage and transport requirements of a traditional vaccine because it delivers the mRNA through an adenovirus rather than a nanolipid.
That is not at all correct. e: https://en.wikipedia.org/w/index.php?title=Messenger_RNA&oldid=790415279 here is the July 2017 wikipedia article on mRNA (which is probably unpozzed because at that point there was no politics attached to mrna).
That's not true. Here's an archive of the same page from 2015. https://archive.is/4OKBO#selection-687.84-687.85 mRNA has always been a mechanism to move instructions from the actual DNA to outside the nucleus. It's never been a mechanism to rewrite DNA (although it is likely that there have been attempts to edit DNA that involve mRNA, but that is not the normal function of mRNA). You are fucking wrong. I took AP biology which isn't much but it's enough to know what mRNA is.
To
translate and form the chemical bonds in protein, the bacterial cell
deploys a piece of extremely complex equipment. The synthesis of
proteins is a two-stage process, since the protein sub-units are
assembled and polymerized, not directly on the gene, but on small
particles in the cytoplasm which serves as assembly lines. the deoxy-
ribonucleic acid text of the gene is therefore first transcribed into
another species of nucleic acid, the so-called ribonucleic acid, by
means of the same four-sign alphabet. This copy, called the 'messen-
ger', associates iwth the particles in the cytoplasm and brings them
the instructions for assembling the protein sub-units in the order
dictated by the nucleic-acid sequence.
Page 276
The logic of life : a history of heredity
by Jacob, François, 1920-2013
Publication date 1976
https://archive.org/details/logicoflifehisto0000jaco_a3n9/page/276/mode/2up
You do need an account to 'borrow' the book. And maybe archive.org is making very convincing edits to their scanned books but that seems wildly unlikely since most people won't investigate past the first internet rag that comes up on google.