This came out around the same time news about the Hot Tub meta, but has been overlooked. I think it merits mention.

If you want to support mental illness, they have several such categories:

Next week, streamers will be able to select from over 350 new tags related to gender, sexual orientation, race, nationality, ability, mental health, and more. The list of tags include transgender, Black, disabled, veteran, and Vtuber, among many others. We will also remove references to “ally” from the LGBTQIA+ tag, and are instead creating a standalone ally tag. These additions won’t change how tagging works and are completely optional. They simply give creators more choices.

Note the very pozzed Black with a capitalized B. How brave and inclusive.

I don't really use Twitch much, but looking into it, you can't exclude tags today, but you can include them. Based on Twitch's past, I doubt they'll add that feature, and definitely would expect them to restrict what you could exclude even if they did.

However, there are certain extensions that apparently support this, so if you are an avid Twitch user, rejoice! Amazon is helping you blacklist all of their mental illness.