I think that was the point of the Jurassic World movies, at least the first one. They basically cleaned the slate and managed to get a fully functional park.

And then they needed bigger "wows" so they kept splicing shit more and more until they created something so ridiculous that it outsmarted them and they weren't able to easily put it down either.

Heck the two Jurassic World Evolution games by Frontier showed how easy it was to fall into the trap yourself, with more insane monsters being let loose to fight each other giving you massive short term boosts but then you have a nightmare of an aggressive creature bred for combat that you have to keep caged somehow.