While I love TNG (even though the cast can’t shut up) and that was the first Star Trek I was familiar with since I was 6 and a fan of reading rainbow when it came out I would say that the original series is my favorite (can happily watch Trek through Enterprise). My dad watched Original Series reruns since as long as I can remember.
The sendoff for the original crew always gets to to me and it just contrast that with writers today who live to crap on or deconstruct the works of better writers. I saw they are making a new blade runner with a delusional man, Disney is making a new Neverending Story, and Netflix is butchering… I mean remaking the Chronicles of Narnia.
One good thing about Star Trek is that I have a lot of books to read. I was at a convention once and a guy had a bunch of Star Trek books for a quarter a piece so I left with a bunch.
I think your example is too small in scale. Salt may be salt but it's not the smaller molecules that are the problem with synthetic food in Star Trek, it's the holistic design of the entire foodstuff and drink.
Wine isn't just alcohol, it's a lot of other intentional and sometimes unintentional ingredients prepared in specific ways then left over time to develop to certain points. Replicators likely miss something here because they are either duplicating a very limited sample previously provided, or only creating the basics and leaving the finished consumable lacking. Traditional wine varies extensively between vintages, even when made with the same ingredients and methods, but that's what many enjoy as it gives each vintage character, or soul. Meanwhile large scale batch productions of modern times lack said character/soul and may still be enjoyable by many, but every bottle under a certain brand and label will likely be the same forever, for better and worse.