One of the points is that something natural and wonderful is being perverted and twisted by something unnatural and deeply selfish.

Like, one of the great tragedies of the unknowable horrors is how desperately that just want children of their own, something pretty normal and brings them closer to us as kin, but are unable to have any due to the state of their existence and the suffering it brings. And the humans in the middle of that process abusing and mutilating everyone in pursuit of worthless goals like "knowledge" just for the sake of it. The Orphan is a literal newborn crawling out of its mother's corpse and is itself just another victim of what was done to the Hamlet.

And the horror of pregnancy is a major theme, the same way it has been for all of human history. Things like "molar pregnancies" have scared the piss out of people forever, and the Japanese have multiple "sankai" named yokai about mothers giving birth to horrible monsters. Its scary not because of some politically driven discourse about "parasites" but because its such a powerful force of nature that human's can scarcely grasp its complexities, and in those complexities lay the ability to go horribly wrong.

Its a game where you eat umbilical cords, give a ghost a miscarriage during a boss fight, and a giant baby beats you to death with its own placenta. Its not fucking subtle about how terrifying and amazing the entire concept of pregnancy is, nor probably the most obvious message of all.

Man should not use his fucking tools or "knowledge" to meddle in it.