The collapse of Rome and before that, Babylon, were not supported by industrial technology. Even with the might of scientific engineering supporting the grift, we are reaching the point where something's got to give. It manifests as palpable unease.

There's a saying in economics: "The market can remain irrational longer than you remain solvent." The current situation, with grifters feeding on the surplus created by industry, can only be maintained so long.

You're right: we can't say when, but things must change.