There has been precedent already set because of counterfeiting; the money was changed to the plastic stuff in the first place because so many places were refusing to accept anything over $20 because it was so fucking bad at the time (and apparently, they're at it again. It was coming out of Dawson Creek/Fort St John BC the last time, I've seen a couple refusal signs pop up recently.)

I'd like to see someone refuse the bills with the black nobody on it. Those I simply deface, and pass to vendors upside down and under another bill.