Now before people latch on and say "you have TDS, you're just a leftist/RINO supporter" let me preface this, I do think he should run and win being president, but the way he is doing it is wrong.
I think he should run as an independent
The people vote for HIM, not the Republican party, if he came out in the speech saying in his own way "I cannot trust or respect the leadership of the Republican party especially when they denied funds to many in the midterms, so I am running independently until that trust can be earned". This would do a lot:
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Deny funding from the MAGA supporters to the Republicans, they'll still have their interest groups but now can't mix the money with grandma's donation.
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Bring more focus on the leaders like mitch because they've now been openly challenged
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Kill any hope for a Republican nominee, anyone trying to run between Biden and Trump would be committing political suicide so those suspicions of Desantis, this will be the ultimate test if he can see the trap. And since he's independent, they cannot screw him in the nomination process.
Just my thoughts, still concerned that Trump doesn't have the best advisors still and not making moves like this .
Which is unfortunate as the reason I suggested this is like you said if there's one guy that could pull off an independent run, it would be Trump. If he could pull it off once just for precedent it feels like it might provide a large enough crack in the uniparty that exists that they spread out too thin trying now stop independents to be effective.