Easy. You start the game and something is tedious. Then you upgrade or optimize something to make it less tedious. You get a dopamine hit.

You create a cool building full of machines networked together to do a previously very complex task. You get a dopamine hit every time you see your cool building on the horizon.

A train passes by filled to the brim with resources you used to have to travel across the map for. You get a dopamine hit.