I'm just about through Scooby-doo Mystery Inc, and they lean a bit on Mayan/Aztec storylines -- what a wonderfully evocative era that seems to have absolutely no hold on mainstream culture! Were there any Manga artists that glommed onto it? Western would be cool too, unless it's about gay Mayans (etc)
As a side-note, French comics (Bande dessinee) had a bunch of wonderful south american stuff, but the one torrent that collected thousands of them seems to be dead.
Not Manga but...Emporers New Groove