It took 2-3 years into the phase III of the dengue fever vaccine trials before ADE was seen in a specific cohort (only those who were yet to be exposed to any variant of dengue). And that's in a disease (dengue) where ADE was known to play a role, so they'd be on high alert for it. And it was still only found late into a phase III of normal timescales. With a bias against looking into ADE/VDE and antigenic original sin effects in this treatment, but with coronovirus vaccines having shown ADE in cats back in the day, I'm unwilling to take it until at least 7 years have gone by. And even then, it will be a protein subunit like novavax, never getting the mRNA shite
Have you taken it? And do you see these as longer term risks that are being properly investigated?
If it took 2-3 years into the phase III of the dengue fever vaccine trials before ADE was seen in a specific cohort (only those who were yet to be exposed to any variant of dengue). And that's in a disease where ADE was known to play a role, so they'd be on high alert for it. And it was still only found late into a phase III. With a bias against looking into ADE/VDE and original sin effects in this treatment, but with coronovirus vaccines having shown ADE in cats back in the day, I'm unwilling to take it until at least 7 years have gone by (and even then, it will be a protein subunit like novavax, never getting the mRNA shite).
Have you taken it? And do you see these as longer term risks that are being properly investigated?
If it took 2-3 years into the phase III of the dengue fever vaccine trials before ADE was seen in a specific cohort (only those who were yet to be exposed to any variant of dengue). And that's in a disease where ADE was known to play a role, so they'd be on high alert for it. And it was still only found late into a phase III. With a bias against looking into ADE/VDE and original sin effects in this treatment, but with coronovirus vaccines having shown ADE in cats back in the day, I'm unwilling to take it until at least 7 years have gone by (and even then, it will be a protein subunit like novavax, never getting the mRNA shite).
Have YOU taken it?