It's not only about what it "looks like".

Like many mechanics in CRPGs, a grid is a proxy for a "realistic" backpack and carry simulation, without being too annoying. You can of course tweak what kind of grid you like to balance between realism and convenience, i.e. whether things stack, whether objects take up multiple "slots", whether objects have weight, etc. etc., and other comments pointed out the pros, but the fundamental idea is messing with objects and inventory management becomes an important part of the game. (and in that case you'd better get it right because it will be memorable to the player for good or bad)

Choosing a list simply means you don't want that mechanic in the game at all. The player is meant to find tons of objects in the world and figure out how to use them - not juggle objects and manage weight like a survival game. "All you want to do is let people pick up and drop stuff or equip things and there's not much else going on" as you say. Then The Inventory isn't part of role-playing at all but simply another status screen. (obviously you can still have things like weight limitations to add challenge)

So your choice depends on what best fits your game and what you/your target-audience likes.

Side note on inventory systems, another somewhat immersive idea was the one used in the 2008 Alone in the Dark remake, where you had to physically store items on your belt, and look around in 3D space to grab/replace items. Personally I think that kind of thing is way too limiting and annoying to work with, but it could fit some games and I wish designers tried uncommon ideas like that more often.

It's not only about what it "looks like".

Like many mechanics in CRPGs, a grid is a proxy for a "realistic" backpack and carry simulation, without being too annoying. You can of course tweak what kind of grid you like to balance between realism and convenience, i.e. whether things stack, whether objects take up multiple "slots", whether objects have weight, etc. etc., and other comments pointed out the pros, but the fundamental idea is messing with objects and inventory management becomes an important part of the game. (and in that case you'd better get it right because it will be memorable to the player for good or bad)

Choosing a list simply means you don't want that mechanic in the game at all. The player is meant to find tons of objects in the world and figure out how to use them - not juggle objects and manage weight like a survival game. "All you want to do is let people pick up and drop stuff or equip things and there's not much else going on" as you say. Then The Inventory isn't part of role-playing at all but simply another status screen.

So your choice depends on what best fits your game and what you/your target-audience likes.

Side note on inventory systems, another somewhat immersive idea was the one used in the 2008 Alone in the Dark remake, where you had to physically store items on your belt, and look around in 3D space to grab/replace items. Personally I think that kind of thing is way too limiting and annoying to work with, but it could fit some games and I wish designers tried uncommon ideas like that more often.