It's more than just obesity, but straight up being out of shape and living on a shitty diet. Endothelial dysfunction. "Chronically low nitric oxide levels, redox equilibrium issues, and excess chronic oxidative stress and chronic inflammation in their vascular endothelium".

Nitric Oxide in the blood vessels makes it much more difficult for spike proteins to attach to vascular endothelial cells (which iirc, are high in ACE2 receptor sites).

It's more than just obesity, but straight up being out of shape and living on a shitty diet. Endothelial dysfunction. "Chronically low nitric oxide levels, redox equilibrium issues, and excess chronic oxidative stress and chronic inflammation in their vascular endothelium"