I'm just about through Scooby-doo Mystery Inc, and they lean a bit on Mayan/Aztec storylines -- what a wonderfully evocative era that seems to have absolutely no hold on mainstream culture! Were there any Manga artists that glommed onto it? Western would be cool too, unless it's about gay Mayans (etc)
As a side-note, French comics (Bande dessinee) had a bunch of wonderful south american stuff, but the one torrent that collected thousands of them seems to be dead.
A recent anime, To Your Eternity may scratch that itch a little bit. It's the story of an immortal shape-shifter who very slowly grows and learns (mostly it learns that life is brutal). Season 1 is set in a vaguely Pacific, vaguely ancient era, and touches on multiple types of cultures. I didn't watch season 2 yet though it wrapped a few months ago.
Ah, thanks -- and this has a manga, which I prefer to anime.