They're not talking about mRNA here.
Dozens of other research groups, scoping out activity along the human genome, also have found that much of our DNA is churning out “noncoding” RNA. It doesn’t encode proteins, as mRNA does, but engages with other molecules to conduct some biochemical task.
Non-coding RNA is not mRNA. It's completely different.
The Perfect Father
Nonfiction about Chris Watts, the guy who had an affair and wanted to start his life over so he murdered his pregnant wife and two young children. He strangled his wife to death and drove for an hour to his work site to bury her, he'd brought along his children who were crying, then he killed them too and stuffed their bodies in oil tanks. Then he went to work like nothing happened.
It got really famous because the wife's friend quickly realized something was wrong mere hours after she was killed, bringing the cops to the house for a welfare check and giving Chris zero time to set the stage for a cover story. There is police body cam footage and you can see Chris behaving guilty as hell and having an internal breakdown of how caught he is.
The Bosch books are really good. I think my favorite might be A Darkness More than Night but The Last Coyote is also great. I fell off the series after awhile because the author has the books set in "real time" so Bosch gets old, retires, comes back, retires, and new characters have to be brought in because he's too old, etc.
My family was huge Doctor Who nerds. As in my grandparents helped get classic Doctor Who episodes digitized because they had recorded them on tape way back when. They toughed out 11th Doctor but gave up by the 12th's poor writing and BBC announced they were going to double down on keeping the writer and pulled out "look a female Doctor" crap.
So the city has so many bum drunks that to prevent them from clogging up hospital services due to alcohol withdrawal (which is one of the most severe drug withdrawals out there), they issue the bums alcohol.
I would normally say let them withdrawal, but you know these fuckers are not the type to quit their addiction even if they end up in the hospital for it.
It's because Microsoft spend 70 billion dollars to buy Activision-Blizzard-King and Bethesda. Microsoft wants that money now. Having medium or small sized game companies not turning much profit (either by being small successes or a little in the red) was previously not an issue because the real goal was to keep up Game Pass subscriptions.
But now Microsoft has this debt, but the market is saturated so there is no way to get a huge load of new Game Pass subscriptions. So Microsoft wants everything to be either making Call of Duty numbers, or to cut things down to the bone by closing entire game studios.
This is also why Microsoft refused to stop production of Redfall even though Arkane Austin warned that it was a mess: because IF Redfall was a success they would be making gangbusters off of a multiplayer game filled with MTX.
Redfall failed, to no one's surprise but Microsoft, so gotta make money this year some other way, so let's close down the studio. Tango, similarly, had a modest success with Hi-Fu Rush and pity that's not Call of Duty numbers, so they were put on the chopping block too.
A lot of people want this big AAA game companies to fail, but to prevent their own failure the companies will sacrifice everything below them first.
It's recommended to pirate Hi-Fi rush because the game has a lot of licensed music, which means Microsoft will likely 1. let it expire entirely, causing the game to be delisted from digital stores or 2. do a clown job of scrubbing the game of its music and replaced by public domain shit, ruining how the game is meant to be experienced
iirc ZeniMax insisted on a big multiplayer game with microtransactions, which Arkane didn't want to do since they make single player games, and they were struggling a lot with it, then Microsoft bought ZeniMax, and instead of realizing "oh this is a disaster heading off a cliff" Microsoft refused to mitigate losses and insisted Redfall keep going. And we know Microsoft is also pushing DEI shit. Probably had a Microsoft employee
And this is just Arkane Austin closing. Arkane has its Austin studio and its Lyon studio. Austin did Dishonored, Prey, and co-developed a couple Wolfenstein games. Lyon did Dishonored 2, Dishonored DOTO, Deathloop, and they're in the middle of making a Blade game.
So I'm not sure if this is getting rid of rot, because Microsoft didn't change from this and Arkane Lyon wasn't affected by this.
If Microsoft had been smart, they would have gotten Arkane Austin playing to its strengths because even if their games weren't selling like hotcakes they would have been useful to draw people into paying for Xbox Game Pass. Just scale things back a bit and not try some big budget multiplayer game from a studio that had zero experience with such a thing and never wanted to do.
Yes, a multiplayer game with microtransaction will be more profitable if it's good enough to get people to buy it and keep them playing to start buying microtransactions, but forcing a game to be multiplayer so you can stuff it with microtransactions is just going to crash and burn.
Scandinavian nations that are often propped up as an example of 'socialism done right' have also been racially homogenous. That is, up until the past couple decades with an influx of immigrants and whatever you do, don't compare the rate of sexual assault per capita with the immigrant population!
Ever see that Grizzly Man documentary? There's an audio of the Timothy Treadwell and his girlfriend getting eaten alive but it's never been released to the public (someone made a fake, and it sounds disturbing enough). Timothy's mother was allowed to keep the recording but she's never listened to it. The documentary's director Werner Herzog was allowed to listen to it, and he immediately tells the mother, "You must never listen to this."
As humans we have conquered much of the world, to the point almost nobody has to worry about being harmed by an apex predator animal. And this safety has led to ignorance and arrogance - a lot of people think they could take on a bear or tiger in a fight. And every so often, this carelessness and stupidity slips out and some fool gets torn apart.
The Twitter bear discourse is so stupid.
"Minor woke elements" the main character has such a MANJAW that I suspected the spelling of "Jesse" instead of "Jessie" was a hint of being trans. Yeah the model actress has a strong chin, but Western game ugly stick smacks the character into "oof" territory, while Control's cover art carefully glows her up to make her seem more like Scarlett Johansson.
It comes with a price. The disposability of women + polygamy culture results in a surplus of single men. Third world shit holes deal with this by having frequent wars with one another to cull the male population.
We can see what happens when you don't have wars, and wind up with far more men available than women in society, by looking at what China has done to its population. Tens of millions of men in a generation who can't date/marry because there aren't enough women to go around, which causes a demand for immigrants. Not to mention the Princess Syndrome this causes women to develop.
They probably got a fat paycheck from Epic Games exclusivity. A quick look says 1.3 million copies sold at least, which is successful from the consumer side of things in that the game certainly found an audience and lots of people played it.
However, if 1.3 million copies still hasn't gotten them to break even yet (sources says they're close) then they must have had high production costs.
If the bastards had made the game available on Steam or even GOG, they would likely have sold a lot more copies by now. It's effectively a console-exclusive game.
Rock and roll was originally a black genre of music that derived from other music developed by black artists (jazz, blues, etc.). Then white people started making rock and roll too and black people less, to the point where Jimmy Hendrix stuck out for being a black dude that did rock and roll. Nowadays almost no black musicians perform rock.
Buuuuuut unless Elvis actually plagiarized, it's not stealing. But it's no secret who he was inspired by, to the point where Eminem (another white guy who got popular making music that's a "black" genre) makes a joke about it in one of his songs.
If you want to read some real entertainment, check out how bitter black people are over East Asians making rap or hip hop music.
...I'm only talking about these remakes of beloved animated classics. Of all the remakes so far, The Little Mermaid is the only one to not do well at the box office.
One can also argue that Pinocchio and Lady and the Tramp also bombed, but since those two were primarily Disney+ streaming movies it's difficult to tell.
I'll believe people are sick of it if the movie bombs.
If people complain and still buy movie tickets, then complaining means nothing.
I'm hoping that people start following through and ignoring these bad movies, because Disney doesn't give a shit about the critical reception if it still gets lots of MONEY. So far I think only the Little Mermaid remake was a notable box office disappointment, which is enough for Disney to say was just a fluke.
Better Help? All else aside, fuck that company. It's a total grift and it's scary because they bribe Youtubers to shill their company to advertise it as a good online therapist source, something that might appeal to a lot of desperate people who don't have the time or transportation to reach an office.
7th gen was also really good for handheld Japanese games. The jump to HD was a major hurdle that affected Japanese developers more, since they tended to be smaller companies in comparison to big AAA Western developers. So most Japanese companies chose to just make games for the handheld systems (DS and PSP, and later 3DS and Vita) with a lot of great titles.
With the Shogun show being a hit, this could have been a GREAT time to make an Assassin's Creed game set in Japan.
And Ubisoft fucked it up lol